TrueCode 100 - Barcoding Reinvented for Throughput and Trust in scRNA-seq Sample Multiplexing

TrueCode¹⁰⁰ is a breakthrough barcoding solution that overcomes a central limitation in scRNA-seq: the lack of scalable, reliable, and easy-to-use tools for multiplexing many biological samples in a single experiment. Developed by scientists from MPG, BIH and UCSF, the proprietary lipid-DNA barcodes bind to cell membranes with unmatched efficiency and stability, eliminating the need for sample washing and reducing hands-on time by over 30-fold—while delivering ultra-precise results.
Unlike existing tools, which are limited to 12 samples, prone to inconsistent data quality, and require complex workflows, TrueCode¹⁰⁰ supports robust multiplexing of many hundreds of samples. This leap in reliability and ease of use unlocks applications like high-throughput drug screens and profiling of low-input samples. Compatible with leading scRNA-seq platforms, TrueCode¹⁰⁰ does not just improve existing workflows—it enables new study designs and expands the market for single-cell analysis across academic, translational, and pharmaceutical research.

A priority patent application has been filed on 10/14/2021.

Licenses to the technology are available from Max Planck Innovation. The lead inventor is available for a meeting and presentation of a non-confidential pitch deck.

Dr. Stefanie Grosswendt
phone: +49 151 4322 1311
stefanie.grosswendt@bih-charite.de