Prozesse und Methoden (inkl. Screening)

Erweiterte Suche

 

Treffer

Ref.-Nr.: 1012-5677-LI

Prozesse und Methoden (inkl. Screening)

File no.: MI-1012-5677-LI-ZE
(liked to MI-1012-4430-LI-ZE describing the generation of neuro- epithelial stem cells as precursors for microtissue generation)

A robust method for producing and analyzing highly homogenous human neural organoids.

Ref.-Nr.: 0204-3324-IKF

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin : Vakzine

"Novel first-in-class intra-nasally applicable safe recombinant "vir4vac" RNA vaccines constitute a very safe and efficacious way of preventing serious infections of respiratory corona and paramyxoviruses as well as other respiratory viruses.“

Ref.-Nr.: 0106-5185-MG

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin : Therapeutika
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Zellen (bezogen)

Remodeling the morphology of mitochondria to manipulate immune cell metabolism and hence reduce immune cell activation and effector functions

Ref.-Nr.: 0041-5034-WT

Prozesse und Methoden (inkl. Screening)

Noble metals are used in various fields of application such as catalysis, jewelry, high technology electronic equipment, equipment for glass industry and many others. As noble metals are rare and hard to extract from the ores or exhausted compounds, many efforts have been undertaken to establish an efficient recycling process. Due to their corrosion resistant properties, noble metals recycling by means of dissolution is limited to the usage of very reactive and harmful chemicals such as Aqua Regia. ...

Ref.-Nr.: 0042-5881-LC

Prozesse und Methoden (inkl. Screening) : Chemische
Neue Materialien

A family of 16-electron binary Ni(0)-stilbene complexes Ni(Rstb)3 as a new class of air-stable Ni(0) (pre)catalysts was developed.

Ref.-Nr.: 0042-5177-LC-WA

Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien

We offer novel phosphenium ligands and corresponding metal complexes (both air stable) that are claimed as substances by granted EP and US patents. The ligands can be prepared in multigram scale by simple direct condensation. The corresponding gold complexes are suitable as homogeneous catalysts in organic synthesis (such as cycloisomerization) that can be easily precipitated and recycled due to their salt properties.

Ref.-Nr.: 0602-5504-LI

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Nukleinsäure (bezogen)

A precise and genetically encoded inhibitor for cell-type selective, inducible and reversible inhibition of protein synthesis

Ref.-Nr.: 1402-5465-LC

Prozesse und Methoden (inkl. Screening) : Chemische

Three novel processes to separate Cl2 from unconverted HCl in the anode outlet stream of a electrochemical gas-phase reactor were developed at the MPI for Dynamics of Complex Technical Systems. The novel processes lead to a higher reaction yield in gas-phase reactor and have an reduced energy demand compared to the Bayer UhDenora state-of-the-art process.

Ref.-Nr.: 0109-4896-LI

Prozesse und Methoden (inkl. Screening)

Fusion Tags Comprising Ubiquitin-like Modifiers and Corresponding Proteases For Protein Purification From Selected Eukaryotic Expression Hosts

Ref.-Nr.: 0402-5782-MG

Prozesse und Methoden (inkl. Screening)

The CRISPR-Cas system is a powerful tool for site-specific genome editing. It allows for the inactivation or substitution of entire genes. However, most hereditary diseases in humans are caused by single point mutations, the correction of which requires only subtle changes to the DNA. Recently, base editors (BEs) were developed that allow the introduction of selective nucleotide substitutions. A Cas9 enzyme is fused to a nucleobase deaminase catalysing C-to-T mutations (by C-to-U deamination) ...

Ref.-Nr.: 1013-4990-IKF

Analytik
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Zellen (bezogen)

An innovative high throughput screening method for measurement of RNA- and DNA-polymerase activity at room temperature, based on time-resolved FRET.

Ref.-Nr.: 0803-5308-IKF

Analytik
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

An innovative chemical inducer of dimerization for studying protein interactions in cells, that overcomes challenges of available dimerizers.

Ref.-Nr.: 0706-5707-IKF

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin : Arzneimittel-Darreichung
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

The LITESEC-T3SS (Light-induced translocation of effectors through sequestration of endogenous components of the T3SS) system represents a novel, fast, specific, and reversible method to control protein secretion into eukaryotic cells, enabling various medicinal and biotechnological applications, such as targeted drug delivery for tumor therapy.

Ref.-Nr.: 1013-5012-IKF

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Zellen (bezogen)

A method for de novo generation and long-term culture of epidermis-derived stems cells in feeder-free conditions and a special cell culture medium for in vitro tissue production, drug discovery and toxicity screenings, and medical applications.

Ref.-Nr.: 0042-4938-LC-WA

Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien

We offer a new family of cationic ligands, namely N-alkyl/aryl pyridiniophosphines. The ligands can be synthesized through a short, scalable, and highly modular route.

Evaluation of their electronic properties evidenced weak σ-donor and quite strong π-acceptor character when used as ancillary ligands.

Ref.-Nr.: 1012-4430-LI

Prozesse und Methoden (inkl. Screening)

File no.: MI-1012-4430-LI-ZE
(liked to MI-1012-5677-LI-ZE describing the generation of human neural microtissues from NECS cells)

A novel precursor population that forms electrophysiologically functional neurons more quickly than protocols starting with hPSCs.

Ref.-Nr.: 1012-4727-IKF

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Zellen (bezogen)

A method to reprogram bone endothelial cells into cells that are able to mediate bone angiogenesis and osteogenesis, opening new avenues to treat osteoporosis.

Ref.-Nr.: 0803-5480-IKF

Analytik
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin : Diagnostika
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

Extremely sensitive, reliable and fast novel KDAC assay, which can be performed in a continuous format. This novel KDAC assay is based on Firefly luciferase harboring an acetylation on an essential active site lysine, incorporated by genetic code expansion. We furthermore offer a bacterial selection system for KDACs, which uses a reporter enzyme inactivated by lysine modifications at an essential active site residue, thereby linking deacetylase activity to a selectable output.

Ref.-Nr.: 0707-5639-MG

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Medizin : Therapeutika
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Nukleinsäure (bezogen)

Antiviral therapy against retroviruses and alphaviruses using tRNALeu(UUA) overexpression

Ref.-Nr.: 0042-4764-LC-WA

Prozesse und Methoden (inkl. Screening) : Chemische
Neue Materialien

An easy process for the facile and permanent immobilization of organocatalysts on nylon textiles was developed.
All of the prepared textile-immobilized organocatalysts (a Lewis basic, a Brønsted acidic, and a chiral organocatalyst) display excellent stability, activity and recyclability for various organic transformations. Very good enantioselectivity (>95:5 enantiomeric ratio) can be maintained for more than 250 cycles of asymmetric catalysis. The flexible construction of fabrics allows ...

Ref.-Nr.: 0901-5500-LC

Analytik
Prozesse und Methoden (inkl. Screening) : Chemische

Fig. 1: shows the efficiency of a stainless steel ozone scrubber comprising a thiosulfate coated surface as described herein versus the efficiency of an identical stainless steel ozone scrubber without a thiosulfate coated surface.

Scientists in the group of Atmospheric Chemistry at the Max Planck Institute for Chemistry in Mainz have developed a novel thiosulfate based ozone scrubber to ensure accurate measurements of trace analytes. It is known from the literature that commercial potassium iodide (KI) containing ozone scrubbers can cause errors in the measurement of carbonyl compounds such as aldehydes and ketones due to byproducts formed from the oxidation of KI. Commercial ozone scrubbers based on sodium thiosulfate ...

Ref.-Nr.: 0402-5469-MG

Analytik
IT / Software / Bioinformatik : Bioinformatik
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

A computer-implemented method that allows calculating concentration ranges of components within complex networks of biochemical reactions.

Ref.-Nr.: 0042-5063-LC

Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien

The ability of hypervalent iodine compounds to act as electrophilic group-transfer reagents has been extensively exploited during the last several years in a variety of synthetically useful transformations
like cyanations and alkynylations. Now it was found, that novel imidazolium sulfuranes, which are isolobal to I(III) species and also depict the key threecenter four-electron bond motive, can be used as an alternative platform for the development of new electrophilic group-transfer reagents.

Imidazolium ...

Ref.-Nr.: 0402-5439-LI

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

SUMOvera enables versatile purification strategies for broad applications in eukaryotic hosts.

Ref.-Nr.: 0105-4794-IKF

Analytik
Prozesse und Methoden (inkl. Screening) : Physikalische

An apparatus and method allowing high throughput collection of X-ray diffraction data at room temperature.

Ref.-Nr.: 1201-4746-LC

Prozesse und Methoden (inkl. Screening) : Chemische
Neue Materialien

We offer the new composite nanomaterial for sodium ion battery cathodes. These carbon-coated nanosized Na3V2(PO4)3 particles embedded in a highly effective mixed conducting porous carbon matrix can be easily prepared by means of facile soft-chemistry based preparation method with a post heat treatment procedure. The resulting cathodes can be charged and discharged in 6 s with high current density of 22 A/g, deliver the specific capacity of 44 mAh/g and ...

Ref.-Nr.: 0214-5029-MG

Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Nukleinsäure (bezogen)
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)

Unique multifunctional oligonucleotide for the ultrafast transcriptome-wide identification of RNA-binding protein (RBP) targets.